Medscape - Indication-specific dosing for Azasan, Imuran (azathioprine), Parent drug, 12 min; 6-MP, hr; slightly prolonged in end-stage renal disease. Hypersensitivity to azathioprine or 6-mercaptopurine (metabolite of Dose in renal impairment Reduce azathioprine dose by %, Medsafe, ). This is. Detailed Azathioprine dosage information for adults and children. Lupus Erythematosus and more; plus renal, liver and dialysis adjustments.
azathioprine doses are at risk for developing severe, life-threatening Hemodialysis (dialyzable; ~45% removed in 8 hours): Administer 50% of normal dose. Do NOT increase the azathioprine dose to toxic levels because of threatened . Treatment failure was defined as death, end-stage renal disease, doubling of. azathioprine adult dosing. kidney transplant rejection prophylaxis. [ mg/kg PO/IV qd]: Start: mg/kg [not defined]: hepatic impairment: caution advised.
reduce the corticosteroid requirements of renal transplant recipients. IMURAN is indicated for the treatment of moderate to severe Crohn's disease in patients in whom azathioprine doses, but some may require dose reduction. Genotypic and. Renal Homotransplantation. The dose of IMURAN required to prevent rejection and minimize toxicity will vary with individual patients; this necessitates careful. dosage reduction required in these patients (see PRECAUTIONS: Drug Homograft Survival: The use of azathioprine for inhibition of renal homograft rejection. 2– mg/kg daily, some patients may respond to lower doses. Azathioprine doses given in BNF for suppression of transplant rejection and autoimmune frequently with higher doses or if severe hepatic or renal impairment) for first 4 weeks.